High lead exposure in two leaded bronze ingot foundry workers
© Song et al.; licensee BioMed Central Ltd. 2014
Received: 9 June 2014
Accepted: 14 October 2014
Published: 1 December 2014
Awareness about lead poisoning in South Korea has increased; however, occupational exposures occurring in small-scale businesses have not been thoroughly investigated. We report two cases of high lead exposure in a leaded bronze ingot foundry.
Two employees, a 54-year-old primary operator and a 46-year-old assistant, at a small-scale metalworking company who had been employed for 18 years and 1 month, respectively, showed elevated blood lead levels (61.1 μg/dL and 51.7 μg/dL, respectively) at an occupational health checkup. Neither worker complained of abnormal symptoms nor signs related to lead poisoning. Health assessment follow-ups were conducted and biological exposure indices of lead were calculated every four weeks. After the initial follow-up assessment, both workers were relocated from the foundry process to the metalworking process. In addition, a localized exhaust system was installed after the second follow-up.
Foundry workers in a small-scale businesses might be at high risk of lead exposure because these businesses might be vulnerable to poor industrial hygiene. Therefore, regular occupational health checkups are required.
KeywordsFoundry Lead exposure Leaded bronze ingot
Bronze is an alloy consisting primarily of copper, but also contains other elements including manganese and aluminum. Leaded bronze (bronze containing lead) increases the plasticity of bronze, simplifies product fabrication, helps retain favorable thermal conductivity, and helps maintain good lubricity ,. As a result, leaded bronze is used for fabrication processes that require precision. When a leaded bronze ingot is melted at high temperatures of 500°C–600°C, lead fumes are created as a by-product. The melting point of lead (327.46°C) is relatively lower than that of other substances; therefore, lead easily sublimates, even at particularly low temperatures. For these reasons, the melting and casting of leaded bronze ingots can result in lead exposure, which occurs as the lead fumes spread throughout the workplace.
The distribution of inhaled lead fumes in the human respiratory tract depends on particle size (typically <5 μm can be damaging), the anatomy of the respiratory tract, mucociliary clearance, and breathing habits . In cases of poor personal hygiene, frequent cigarette smoking, or poor environmental conditions, lead fumes can be absorbed orally by the human body, and lead intake can cause lead poisoning in some individuals. Acute or chronic symptoms of lead poisoning can manifest in multiple systems of the body including the central and peripheral nervous systems, erythropoietin system, cardiovascular system, musculoskeletal system, immune system, and/or reproductive system .
When lead absorbed by the human body enters the bloodstream, the blood lead level (BLL) rises. Several guidelines for BLL monitoring have been proposed. The Occupational Safety and Health Administration recommends that individuals avoid tasks that lead to further lead exposure if their BLL is ≥60 μg/dL (or reaches a mean level of 50 μg/dL on three or more tests) . In South Korea, guidelines for periodic occupational health checkups recommend reducing lead exposure if the BLL is ≥30 μg/dL and that these individuals receive a checkup every 2 months until two consecutive BLLs readings are <30 μg/dL .
Reported cases of occupational lead poisoning in South Korea include lead battery poisoning (1972 and 1986), the Janghang Smelting lead poisoning incident (1978), and the Banwol Industrial Complex lead poisoning incident (1983) -. Since these incidents, legal regulations and policies have been strengthened and regular measurements of workplace environmental levels and health examinations have been performed; as a result, the incidence of lead poisoning has decreased -. However, incidences of lead poisoning have still been reported in a small-scale businesses with long-term employees because legal management is difficult . To our knowledge, no reported cases of high-lead exposure among leaded bronze ingot foundry workers are present in South Korea. Here, we present two cases with increased BLLs after working in a leaded bronze ingot foundry.
Occupational and medical history
The first patient was a 54-year-old man with 18 years of experience working in a foundry as a primary operator. He had been employed at a hydraulic equipment manufacturing company for the past 10 years and worked at the melting furnace and in molding frame department. He had a history of hyperthyroidism and smoked five pack-years, but had no family history of disease.
The second patient was a 46-year-old man with seven, three, and seven years of experience plating, driving a taxi, and driving a truck, respectively. He had been employed at the same manufacturing company as an assistant operator at the melting furnace and in molding frame department for one month. He had no history of illness or any hereditary diseases, but smoked 20 pack-years.
Neither patient had a history of herbal or health supplement intake. During the initial occupational health checkup, neither patient complained of abnormal symptoms such as muscle weakness, paresthesia, abdominal colicky pain, nausea, vomiting, diarrhea, or constipation. No abnormalities in the heart or respiratory sounds were noted upon auscultation. In addition, no tenderness or distension was observed during the abdominal examination. Moreover, no indications of Burton’s lines around the gums were present, and neither patient showed signs of pallor, petechiae, dyspnea on exertion, fatigue, malaise, or other symptoms related with anemia.
Chemical composition of raw materials
Chemical composition (%)
Bulk sampling* Carbon
Bulk sampling* Borax
Measurements in the work environment
Measured results (mg/m3)
OEL (TWA, mg/m3)
Initial measurement December 9, 2013
Follow-up measurement February 4, 2014
Area sample of the melting furnace
Area sample of the molding frame
Health assessment and biological exposure indices
Clinical laboratory results
Blood lead level (μg/dL)
Initial sampling (Dec. 24, 2013)
1st follow-up sampling (Jan. 16, 2014)
2nd follow-up sampling (Feb. 21, 2014)*
3rd follow-up sampling (Mar. 24, 2014)*
4th follow-up sampling (Apr. 24, 2014)*
Blood analysis (at initial sampling)
Urinary analysis (at 1st follow-up sampling)
Urine lead level (μg/g creatinine)
Blood pressure (at initial sampling)
Systolic blood pressure (mmHg)
Diastolic blood pressure (mmHg)
Blood cell morphology
1st follow-up sampling (Jan. 16, 2014)
Slight platelet aggregation
2nd follow-up sampling (Feb. 21, 2014)*
Slight platelet aggregation
3rd follow-up sampling (Mar. 24, 2014)*
4th follow-up sampling (Apr. 24, 2014)*
The white blood cell differential counts for both workers were within the normal range. The results of a blood cell morphology test in the primary operator showed slight platelet aggregation at the first and second follow-up tests, but this value normalized by the third and fourth follow-up tests. However, the blood cell morphology test results for the assistant remained normal. The primary operator had an elevated gamma-glutamyl transpeptidase level (57 U/L) at the initial health checkup, but this value normalized in the follow-up tests reaching 42 U/L by the third follow-up.
After the first follow-up, the BLL of three workers in the metalworking process (two workers in charge of the machining center tooling process and one worker in charge of the CNC process) and the on-site supervisor were also measured. Their BLLs were 22.66 μg/dL, 29.28 μg/dL, 20.98 μg/dL, and 26.70 μg/dL, respectively, with an average BLL of 24.91 ± 3.78 μg/dL.
Elevated BLL is associated with psychological symptoms such as depression, anxiety, cognitive deficit, and memory loss ,. As such, psychological tests were performed by trained psychologists at the first follow-up. These tests included a digit span to evaluate attention, the Seoul Verbal Learning Test to evaluate verbal memory, a verbal fluency test, the Stroop test, a psychomotor speed measurement, a working memory test using the Korean-Wechsler Adult Intelligence Scale to evaluate frontal lobe function, the Korean version of the Boston Naming Test to evaluate language skills, the Rey-Osterrieth complex figure test to evaluate visuospatial skills, and the Hamilton Depression Scale and Beck Depression Scale to evaluate mood status. Slightly reduced psychomotor speed on the Korean-Wechsler Adult Intelligence Scale (raw score 41/135, percentile score 5) and a reduced interference score in the Stroop test (interference score 11, percentile score 10) were noted in the primary operator; however, all other results were normal.
Nerve conduction test
The primary operator complained of weakness while using chopsticks at the fourth follow-up; therefore, a nerve conduction velocity test was performed by a trained neurologist at the fourth follow-up. Results were consistent with carpal tunnel syndrome and included decreased sensory nerve action potential, slow sensory nerve conduction velocity in the forearm (wrist and palm) wrist segments of the right median nerve, prolonged terminal latency, decreased compound muscle action potential in the wrist (elbow and elbow) axilla segments of the right median nerve, and a prolonged F-wave in the right median nerve. Nerve conduction tests were not performed in the assistant because he left the company before the fourth follow-up.
This report documents two cases of high lead exposure in workers from a leaded bronze ingot foundry. In 1978, lead poisoning was reported in a major smelting factory located in Janghang, South Korea. Severely lead poisoned workers from this incident were admitted to the hospital to chelate the lead and lower their high BLLs . Soon after, in October 1983, lead poisoning was reported in the Banwol Industrial Complex in South Korea. One hundred and one lead workers in seven factories that handled lead daily (six litharge-making factories and one storage-battery factory) were investigated. Among these, 33 cases of lead poisoning (BLL >80 μg/dL) and 36 cases of high lead absorption (BLL >60 μg/dL) were diagnosed . In September 1986, 66 out of 258 lead workers in a storage-battery factory in South Korea were screened for lead poisoning and referred for laboratory tests; 29 of these workers were diagnosed with lead poisoning and 12 had severe lead poisoning that required hospital admission to chelate the lead and lower their BLLs .
The most important aspect in treating lead poisoning is eliminating the source of lead exposure. However, eliminating the source of lead can be very difficult depending on the socioeconomic challenges involved. The Occupational Safety and Health Administration and Association of Occupational and Environmental Clinics have published guidelines of the clinical symptoms of lead poisoning to facilitate diagnosis and set standards for its management in suspected cases of lead exposure ,. In general, BLL is used as an important biological indicator in clinical evaluations, worksite monitoring, and public health.
Shortly after lead is inhaled or ingested, it can enter the bloodstream and travel to soft tissues. After several weeks, the absorbed lead can be deposited and stored in mineralizing tissues such as bones. In the current study, we were unable used X-ray fluorescence to measure the workers’ long-term lead exposure. With X-ray fluorescence, we hypothesize that the bone lead level of the primary operator was higher than that of the assistant, considering his long exposure. Lead can also interfere with heme biosynthesis by inhibiting d-aminolevulinic acid dehydratase and ferrochelatase activity, thus increasing blood and plasma d-aminolevulinic acid and free erythrocyte protoporphyrins , which leads to anemia. In the primary operator and assistant, hemoglobin levels were 15.8 g/dL and 16.3 g/dL, respectively, which are both within the normal range; thus, it was assumed that lead exposure did affect the enzymatic heme pathway of these two workers. Lead poisoning may also result in abdominal pain, loss of appetite, vomiting, nausea, constipation, and/or diarrhea. No specific symptoms or signs were found in the review the patients’ history or during the physical examination. Lead poisoning can also cause peripheral nerve damage that causes muscle weakness. In addition, behavioral changes vision and hearing impairment are possible. At very high BLLs, lead can affect the brain causing convulsions, a coma, and even death . Moreover, lead can inhibit the N-methyl-D-aspartate receptor that is related with hippocampus-mediated learning and memory resulting in defects in the memory processes of the brain. Lead can also cause deficits in neurotransmission, disrupt neurotransmission and intracellular Ca2+ dynamics, and ultimately result in neurotoxicity . Among the current cases, the primary operator showed a slightly reduced psychomotor speed and interference control during psychological assessment and had a right median nerve abnormality that is consistent with carpal tunnel syndrome.
Clinical symptoms of lead poisoning are typically associated with chronic lead poisoning; thus, cases of acute lead poisoning are difficult to diagnose. In certain cases, lead poisoning can manifest asymptomatically . In the present cases, aside from subtle neurologic abnormalities in the primary operator, no specific clinical findings of lead poisoning were evident for either of the workers. Although we cannot eliminate the possibility that the aforementioned abnormal findings in the primary operator were the result of chronic lead exposure, the symptoms were not severe. Moreover, the associations between reduced motor conduction, short-term memory loss, and impaired visual-motor coordination with lead poisoning have not been evaluated . Although our subjects had no clinical symptoms, subclinical changes such as behavioral changes, subclinical hypertension, or a subclinical tumor might have existed.
The assistant presented with a higher BLL than that of the primary operator at all follow-up evaluations, but not at the initial assessment. In the workplace, the assistant continuously stood in front of the molding frame during the molding frame preparation with his head bent towards the frame; therefore, his mask was in close contact with the molten metal and it was assumed that he inhaled a greater proportion of the lead fumes. Furthermore, the level of work experience might have influenced the differences in the BLLs between the primary and assistant operators. In addition, although an exhaust system was installed above the furnace, no exhaust system was present above the molding frame; thus, these workers were continuously exposed to lead fumes while transferring the molten metal during the casting process.
After the first follow-up, the primary and assistant operators had BLLs of approximately 40 μg/dL and were relocated the CNC department. Nevertheless, the BLL of the other CNC workers were found to be >20 μg/dL, which is much higher than the average in South Korea of 1.77 μg/dL that was reported in 2011 . These findings suggest the possibility of background lead exposure at the work site. The smelting and casting processes and CNC/machining center tooling processes were separated by a wall; therefore, the BLLs of employees working in processes other than smelting likely did not become exposed to lead from the smelting process.
Metal cutting occurs at temperatures between 214°C–594°C . As such, lead fumes caused by sublimation can also cause health damage in high-temperature cutting operations . It is possible that the BLL of workers in other processes increased because of these lead fumes. Another possibility is the absorption of lead through the digestive tract and skin. One expended furnace had been left in the factory, and sand was strewn on the floor of the work site. We measured a lead content of >10% in the expended furnace and sand. Lead in these items may have contaminated the workers’ hands, clothes, and any drinks consumed in the workplace. Relevant studies have reported that 5%–10% of the lead absorbed through the digestive tract is ultimately absorbed by the human body . Therefore, workers at the present site may have absorbed lead not only through the respiratory tract but also through the skin or mouth.
The atmospheric lead concentration in this work environment was less than the Ministry of Labour standard (0.05 mg/m3), but more than the Korean environmental atmospheric standard (0.0005 mg/m3) and EPA standard (0.00015 mg/m3) ,. Since the atmospheric lead concentration does not reflect skin absorption, bodily accumulation, or personal hygiene maintenance, the correlation between the atmospheric lead concentration and BLL is considered weak . In the present cases, the atmospheric lead concentration does not reflect the skin and oral exposure to lead dust at the work site. In addition, exposure to high concentrations of lead fumes during smelting work is assumed to occur while pouring molten metal into molding frames. Such tasks occur over a relatively short time (5–10 min per session, 5–6 sessions per day). Work environment measurements are collected as the mean lead exposure over 8 h; thus, this measurement may not have accurately reflected their instantaneous exposure to high lead concentrations. In addition, during the 8-h measurement period, the number of actual work sessions may have affected the measured results.
In the present work site, the lack of the MSDS for the primary material was substituted with an inspection certificate. Nevertheless, an MSDS of the reducing agents were not provided. Moreover, despite the fact that the furnace process requires a level 1 dust mask, workers at this company were only provided with level 2 dust masks. In addition, protective gear was worn inconsistently ,. The work site near the furnace was also strewn with waste, such as that from the expended furnace, and high concentrations of lead were detected in this waste. Furthermore, exhaust systems were not properly installed at the work site.
Taken together, to help prevent lead exposure, all companies must be equipped with an MSDS for all materials used in their manufacturing process, and the owners and workers of these companies must all be aware of the contents of the MSDS. Furthermore, to minimize lead exposure, appropriate protective gear, including level 1 dust masks and protective goggles, should always be provided and worn, and an appropriate exhaust system must be installed. In addition, to eliminate contamination by lead dust, the work site should be cleaned daily with a vacuum cleaner or water. Smoking and eating/drinking should be prohibited at the work site to protect the workers, and facilities that promote personal hygiene by including sinks, baths, and washing machines should be made available. In addition, face washing and bathing should be mandatory after daily work. Employees should also be educated on the above materials, and any notifications regarding handling precautions and personal protection should be displayed in an easily visible location. Moreover, work environment measurements and specialist checkups should be conducted regularly to monitor the degree of lead exposure among workers. In cases of high lead exposure, appropriate intervention methods should be immediately performed to protect the health of workers .
Because our report only conducted follow-ups and observed two workers with high lead exposure after an occupational health checkup, we could not adequately investigate the source of lead exposure with respect to the entire work site or compare the lead exposure throughout the facility. Thus, future epidemiological studies on the workers at the present work site are needed.
To our knowledge, this is the first report of a high lead exposure in a leaded bronze ingot foundry in South Korea. Although the two workers studied here did not demonstrate clinical symptoms of lead poisoning, the BLLs of these workers did reach a maximum of 69 μg/dL, and even the other workers at the metalworking process, which were isolated from the foundry, exhibited a relatively high mean BLL of 24.91 ± 3.78 μg/dL. To prevent lead exposure among employees in smaller factories, appropriate periodic occupational health checkups and functional environment protection measurements to protect the workers’ health are needed.
We performed a retrospective chart review and collected no personal identification data. The Institutional Review Board of Inje University Busan Paik Hospital approved our waiver of written informed consent and review exemption (IRB No. 14–0115).
- Puttlitz KJ, Stalter KA: SN-AG and SN-AG-X Solders and Properties. In Handbook of Lead-Free Solder Technology for Microelectronic Assemblies. CRC Pess, New York; 2004:273.View ArticleGoogle Scholar
- Mel S: Lead and Alloys. In Encyclopedia of Materials, Parts and Finishes. 2nd edition. Edited by: Mel S. CRC Press, New York; 2012:349–350.Google Scholar
- Andrea H, Harun P, Brock TH: Aerosols – Dusts, Fumes and Mists [MAK Value Documentation, 1999]. In The MAK Collection for Occupational Health and Safety. Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim; 2012:271–278.Google Scholar
- Jie L, Goyer RA, Waalkes MP: Toxic Effects of Metals. In Casarett&Doull’s Toxicology : The Basic Science of Poisons. 7th edition. Edited by: Klaassen CD. McGraw-Hill, New York; 2008:943–947.Google Scholar
- OSHA Lead Standards. 2014.Google Scholar
- Lead and inorganic compounds, as Pb In Practical Guideline for Medical Examination of Employee (translated by Song YJ). Korea Occupational Safety and Health Agency, Incheon; 2013:222.Google Scholar
- Lee JS, You IS: A study on contents of heavy metal in water, soil, rice and urine of inhabitants along the Kum river. Korean J Occup Environ Med 1992, 18(1):69–75. KoreanGoogle Scholar
- Lee IJ, Ahn KD, Jo KS, Kim NS: A study on the soil pollution in lead industry. J Korean Soc Occup Environ Hyg 2004, 14(3):290–300. KoreanGoogle Scholar
- Kang PG, Kim YB, Ahn IS, Lee GJ: Occupational lead exposure of storage battery industry workers in Korea. Korean J Occup Environ Med 1998, 10(4):438–449. KoreanGoogle Scholar
- Industrial Safety and Health Act. ᅟ, Seoul; 2012.Google Scholar
- Choi JW, Kim NS, Cho KS, Ham JO, Lee BK: The change of air lead concentrations in litharge making and smelting industries. J Korean Soc Occup Environ Hyg 2010, 20: 10–18. Korean with English abstractGoogle Scholar
- Lee BK: Occupational Health Management in the Lead Industry: The Korean Experience. Saf Health Work 2011, 2(2):87–96.View ArticlePubMedPubMed CentralGoogle Scholar
- Koo BH, Kim YK, Lee SG, Kang DM, Kim JE: Detection of Cases and a Cause of Lead Exposure in Korean Steel Company. Korean J Occup Environ Med 2012, 24(4):441–448. Korean with English abstractGoogle Scholar
- George R: Metals and Related Minerals and Ores. In Archaeomineralogy. 2nd edition. Edited by: George R. Springer, New York; 1999:144.Google Scholar
- Bouchard MF, Bellinger DC, Weuve J, Matthews-Bellinger J, Gilman SE, Wright RO, Schwartz J, Weisskopf MG: Blood lead levels and major depressive disorder, panic disorder, and generalized anxiety disorder in US young adults. Arch Gen Psychiatry 2009, 66(12):1313–1319.View ArticlePubMedPubMed CentralGoogle Scholar
- Medical Management Guidelines for lead-Exposed Adults. 2014.Google Scholar
- Lead Toxicity. 2014.Google Scholar
- Guideline:Lead on construction projects. 2014.Google Scholar
- Neal AP, Guilarte TR: Mechanisms of lead and manganese neurotoxicity. Toxicol Res 2013, 2: 99–114.View ArticleGoogle Scholar
- Moline JM, Landrigan PJ: Lead. In Textbook of Clinical Occupational and Environmental Medicine. 2nd edition. Edited by: Linda R, Cullen MR, Carl Andrew B, Relich CA. Elsevier Saunders, Phildelphia; 2005:967–978.Google Scholar
- Korean National Environmental Health Survey; The First Stage (2009~2011). ᅟ, Incheon; 2011.Google Scholar
- Tanikic D, Manic M, Radenkovic G, Manic D: Metal cutting process parameters modeling and artificial intelligence approach. J Sci Ind Res India 2009, 68: 530–539.Google Scholar
- Richard L: Metals. In Current Occupational & Environmental Medicine. 4th edition. Edited by: Joseph LD. McGraw-Hill, New York; 2007:413–438.Google Scholar
- Enforcement Decree of the Framework Act on Environmental Policy ᅟ 2012, ᅟ: ᅟ. [http://www.moleg.go.kr/english/korLawEng?pstSeq=52647][Accessed 2 August 2014]Google Scholar
- National Ambient Air Quality Standards for lead; Final rule. ᅟ, ᅟ; 2008.Google Scholar
- Park SG, Kim KJ, Chang SH: A study on the Correlation Between the Lead Concentration in Air and in Blood among Lead Workers. Korean J Occup Environ Med 1991, 3(1):98–103. KoreanGoogle Scholar
- Respiratory protection guideline (translated by Song YJ). 2014.Google Scholar
- Guideline for Health management of Workers exposed by lead and inorganic lead (translated by Song YJ). 2014.Google Scholar
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