The Relationship of Liver Function Tests to Mixed Exposure to Lead and Organic Solvents

Table 4 Comparison of geometric means of the AST, ALT, and GGT unit: IU/L

		Control (n=125)	Solvent-exposed		Lead-exposed (n=257)	Mixed exposure (n=45)	p-value
		Control (n=125)	TCE ^§co-exposed (n=82)	TCE non-exposed (n=84)	Lead-exposed (n=257)	Mixed exposure (n=45)	p-value
No adjustment
	AST^*	21.9±1.3^a	22.6±1.4^a	23.2±1.3^a	23.4±1.4^a	26.9±1.3^b	0.005^¡«
	ALT^†	23.4±1.5^a	22.7±1.6^a	23.2±1.6^a	24.5±1.6^a	29.5±1.6^b	0.028^¡«
	GGT^‡	33.9±1.9^a,b	30.0±1.7^a	33.2±1.8^a,b	38.9±2.0^b	39.8±1.5^b	0.009^¡«
After adjustment
	AST	22.6±1.0^a	22.8±1.0^a	23.8±1.0^a	23.5±1.0^a	28.9±1.0^b	<0.000^¶
	ALT	23.6±1.0^a	24.3±1.1^a,b	23.6±1.1^a	24.0±1.0^a	30.0±1.1^b	0.032^¶
	GGT	34.6±2.0^a,b	30.0±1.7^a	33.2±1.8^a,b	39.1±2.0^a,b	39.9±1.6^b	0.021^¶

^*Aspartate aminotransferase, ^†Alanine aminotransferase, ^‡Gamma glutamyl transferase, ^§Trichloroethylene.
^∥p-values were tested by one-way ANOVA. and the post-hoc test was based on Duncan's method.
^¶p-values were tested by general linear model adjusted for age, body mass index, work duration, smoking, and alcohol intake by general linear model. The post-hoc test was based on Bonferroni's method.
^a,bThe same letters indicate a non-significant difference between groups.

ISSN: 2052-4374