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Table 5 Number of workers with abnormal liver function index values, odds ratios, and 95% confidence intervals according to the cut-off value

From: The Relationship of Liver Function Tests to Mixed Exposure to Lead and Organic Solvents

   

Number (%)

OR *

95% CI †

The cut-off value of AST‡, ALT§, and GGT∥ were taken to be 40 IU/L, 42 IU/L, and 63 IU/L

AST

Control

 

4 (3.2)

  
 

Solvent-exposed

TCE¶ co-exposure

3 (3.7)

1.02

0.21-4.96

 

Solvent-exposed

TCE non-exposure

2 (2.4)

0.84

0.15-4.76

 

Lead-exposed

 

21 (8.2)

2.66

0.87-8.17

 

Mixed exposure

 

2 (4.4)

1.46

0.25-8.57

ALT

Control

 

12 (9.6)

  
 

Solvent-exposed

TCE co-exposure

8 (9.9)

1.36

0.49-3.78

 

Solvent-exposed

TCE non-exposure

10 (11.9)

1.36

0.54-3.45

 

Lead-exposed

 

35 (13.6)

1.49

0.72-3.06

 

Mixed exposure

 

7 (15.6)

1.55

0.23-4.54

GGT

Control

 

24 (19.2)

  
 

Solvent-exposed

TCE co-exposure

8 (9.9)

0.52

0.20-1.34

 

Solvent-exposed

TCE non-exposure

8 (9.5)

0.50

0.20-1.22

 

Lead-exposed

 

63 (24.5)

1.32

0.75-2.32

 

Mixed exposure

 

7 (15.6)

0.97

0.35-2.66

The cut-off value of AST, ALT, and GGT were taken to be 30 IU/L, 30 IU/L, and 40 IU/L

AST

Control

 

15 (12.0)

  
 

Solvent-exposed

TCE co-exposure

8 (9.9)

0.80

0.31-2.09

 

Solvent-exposed

TCE non-exposure

9 (10.7)

1.00

0.31-2.45

 

Lead-exposed

 

44 (17.1)

1.42

0.75-2.70

 

Mixed exposure

 

15 (33.3)

4.39

1.86-10.40

ALT

Control

 

41 (32.8)

  
 

Solvent-exposed

TCE co-exposure

18 (22.2)

0.94

0.45-1.94

 

Solvent-exposed

TCE non-exposure

22 (26.2)

0.81

0.41-1.58

 

Lead-exposed

 

89 (34.6)

1.04

0.64-1.71

 

Mixed exposure

 

19 (42.2)

1.73

0.78-3.82

GGT

Control

 

41 (32.8)

  
 

Solvent-exposed

TCE co-exposure

24 (29.6)

1.27

0.63-2.56

 

Solvent-exposed

TCE non-exposure

25 (29.8)

1.13

0.59-2.18

 

Lead-exposed

 

104 (40.5)

1.35

0.83-2.19

 

Mixed exposure

 

18 (40.0)

2.10

0.94-4.68

  1. *Adjusted for age, work duration, body mass index, smoking, alcohol by binary logistic regression model.
  2. †Confidence interval, ‡Aspartate aminotransferase, §Alanine aminotransferase, ∥Gamma glutamyl transferase, ¶Trichloroethylene.