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Table 5 Number of workers with abnormal liver function index values, odds ratios, and 95% confidence intervals according to the cut-off value

From: The Relationship of Liver Function Tests to Mixed Exposure to Lead and Organic Solvents

    Number (%) OR * 95% CI
The cut-off value of AST, ALT§, and GGT were taken to be 40 IU/L, 42 IU/L, and 63 IU/L
AST Control   4 (3.2)   
  Solvent-exposed TCE co-exposure 3 (3.7) 1.02 0.21-4.96
  Solvent-exposed TCE non-exposure 2 (2.4) 0.84 0.15-4.76
  Lead-exposed   21 (8.2) 2.66 0.87-8.17
  Mixed exposure   2 (4.4) 1.46 0.25-8.57
ALT Control   12 (9.6)   
  Solvent-exposed TCE co-exposure 8 (9.9) 1.36 0.49-3.78
  Solvent-exposed TCE non-exposure 10 (11.9) 1.36 0.54-3.45
  Lead-exposed   35 (13.6) 1.49 0.72-3.06
  Mixed exposure   7 (15.6) 1.55 0.23-4.54
GGT Control   24 (19.2)   
  Solvent-exposed TCE co-exposure 8 (9.9) 0.52 0.20-1.34
  Solvent-exposed TCE non-exposure 8 (9.5) 0.50 0.20-1.22
  Lead-exposed   63 (24.5) 1.32 0.75-2.32
  Mixed exposure   7 (15.6) 0.97 0.35-2.66
The cut-off value of AST, ALT, and GGT were taken to be 30 IU/L, 30 IU/L, and 40 IU/L
AST Control   15 (12.0)   
  Solvent-exposed TCE co-exposure 8 (9.9) 0.80 0.31-2.09
  Solvent-exposed TCE non-exposure 9 (10.7) 1.00 0.31-2.45
  Lead-exposed   44 (17.1) 1.42 0.75-2.70
  Mixed exposure   15 (33.3) 4.39 1.86-10.40
ALT Control   41 (32.8)   
  Solvent-exposed TCE co-exposure 18 (22.2) 0.94 0.45-1.94
  Solvent-exposed TCE non-exposure 22 (26.2) 0.81 0.41-1.58
  Lead-exposed   89 (34.6) 1.04 0.64-1.71
  Mixed exposure   19 (42.2) 1.73 0.78-3.82
GGT Control   41 (32.8)   
  Solvent-exposed TCE co-exposure 24 (29.6) 1.27 0.63-2.56
  Solvent-exposed TCE non-exposure 25 (29.8) 1.13 0.59-2.18
  Lead-exposed   104 (40.5) 1.35 0.83-2.19
  Mixed exposure   18 (40.0) 2.10 0.94-4.68
  1. *Adjusted for age, work duration, body mass index, smoking, alcohol by binary logistic regression model.
  2. Confidence interval, Aspartate aminotransferase, §Alanine aminotransferase, Gamma glutamyl transferase, Trichloroethylene.