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Table 1 Detection rate, sensitivity, specificity and positive predictive value of computed tomography (CT) screening sturdies [17]

From: Review of carcinogenicity of asbestos and proposal of approval standards of an occupational cancer caused by asbestos in Korea

Study Lung cancer + Lung cancer - Total Results
Sone et al, 1998 [15], Sone, 2000 [18]
 Initial screening in 1996 Detection rate 0.4 %
 CT + 25 305 330 Sensitivity 57 %
 CT - 19 5965 5984 Specificity 95 %
 Total 44 6270 6314 Predictive value 8 %
 First annual repeat in 1997 Detection rate 0.6 %
 CT + 28 169 197 Sensitivity 85 %
 CT - 5 4823 4828 Specificity 97 %
 Total 33 4992 5025 Predictive value 14 %
 Second annual repeat in 1998 Detection rate 0.2 %
 CT + 9 164 173 Sensitivity 100 %
 CT - 0 4867 4867 Specificity 97 %
 Total 9 5031 5040 Predictive value 5 %
Henschke et al, 1999 [19]
 Initial screening Detection rate 2.7 %
 CT + 27 206 233 Sensitivity 100 %
 CT - 0 767 767 Specificity 79 %
 Total 27 973 1000 Predictive value 12 %
 First annual repeat Detection rate 0.6 %
 CT + 6 24 30 Sensitivity 100 %
 CT - 0 970 970 Specificity 98 %
 Total 6 994 1000 Predictive value 20 %
Vehmas et al, 2000 [20]
 Initial screening Detection rate 0.8 %
 CT + 5 60 65 Sensitivity 100 %
 CT - 0 537 537 Specificity 90 %
 Total 5 597 602 Predictive value 8 %
  1. CT+ means the lung cancer was detected by CT
  2. CT- means the lung cancer was not detected by CT
  3. Lung Cancer + means the lung cancer was diagnosed by biopsy
  4. Lung Cancer- means the lung cancer was not diagnosed by biopsy