Risks of borderline liver enzyme abnormalities to the incidence of impaired fasting glucose and diabetes mellitus: a 7 year follow up study of workers

Table 3 Relative risks to the incidence of IFG or DM according to initial liver enzyme levels

Levels of initial liver enzyme	Blood glucose level		Relative Risk	p-value^*
Levels of initial liver enzyme	Staying normal	IFG or DM	Relative Risk	p-value^*
AST (IU/L)				0.305
A^a	487 (88.2)	65 (11.8)	1
B^b	12 (80.0)	3 (20.0)	1.69
R^c	9 (81.8)	2 (18.2)	1.54
ALT (IU/L)				0.011
A	418 (90.3)	45 (9.7)	1
B	35 (70.0)	15 (30.0)	3.09
R	55 (84.6)	10 (15.4)	1.59
γ-GTP (IU/L)				0.000
A	459 (90.2)	50 (9.8)	1
B	19 (65.5)	10 (34.5)	3.52
R	30 (75.0)	10 (25.0)	2.55
Number of abnormal liver enzymes				0.000
0	396 (91.2)	38 (8.8)	1
1	72 (80.0)	18 (20.0)	2.27
2	32 (76.2)	10 (23.8)	2.70
3	8 (66.7)	4 (33.3)	3.78

IFG impaired fasting glucose, DM diabetes mellitus, AST aspartate aminotransferase, ALT alanine aminotransferase, γ-GTP gamma-glutamyltransferase
^aA was defined as ≤40 IU/L for AST, ≤35 IU/L for ALT, or ≤63 IU/L in males or ≤35 IU/L in females for γ-GTP
^bB was defined as 41–50 IU/L for AST, 36–45 IU/L for ALT, and 64–77 IU/L in males or 36–45 IU/L in females for γ-GTP
^cR was defined as ≥51 IU/L for AST, ≥46 IU/L for ALT, and ≥78 IU/L in males or ≥46 IU/L in females for γ-GTP
^*Chi-square test

ISSN: 2052-4374