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Table 4 Risks of leukemia (excluding CLL) in epidemiological studies of nuclear workers

From: Radiation-related occupational cancer and its recognition criteria in South Korea

     

Mean

  

Number of event cases

  

Country

Study

Cohort size

Exposure

period

Follow-up

period

cumulative

dose

(mSv)

Person

years

Types of events

ERR

(95% CI)

SMR or SIR (95% CI)

15-country

Cardis et al. (2007) [23]

407,391

1943-2000

1943-2000

19.4

5,192,710

Mortality

196

1.93

b(<0, 7.14)

-

3-country

(INWORKS)

Leuraud et al. (2015) [24]

308,297

1943-2005

1944-2005

15.9mGy

8,220,000

Mortality

531

2.96 (1.17, 5.21)

-

Korea

aAhn et al. (2008) [64]

79,679

1984-2004

1984-2004

1992-2004

1989-2005

6.1

6.1

633.159

415,298

Mortality

Morbidity

9

14

16.8

b(-34, 149) 15.8

b(-31, 108)

0.59 (0.28, 1.06)

 

Jeong et al. (2010) [65]

8,429

1978-2005

1992-2005

19.86

63,503

Incidence

3

NC

1.34 (0.27, 3.92)

U.K.

Muirhead et al. (2009) [63]

174,541

1946-2001

1965-2001

24.9

3,900,000

Mortality

Incidence

198

234

1.71 (-0.17, 4.92) 1.78 (-0.06, 4.99)

0.89 (0.76, 1.03)

U.S.

Howe et al. (2004) [66]

53,698

Mid-1960s

1979-1997

25.7

698,051

Mortality

26

5.67 (-2.56, 30.4)

a

1.07 (0.71, 1.53)

Canada

Zablotska et al. (2014) [67]

45,316

1951-1994

1956-1994

21.64

613,648

Mortality

17

9.79 (<-1.49, 107)

0.78 (0.45, 1.25)

France

Flamant et al. (2013) [30]

59,021

1950-2004

1968-2004

16.1

1,467,611

Mortality

60

3.96

b(<0, 16.82)

-

Germany

Merzenich et al. (2014) [68]

8,972

1966-2008

1991-2008

29.5

130,737

Mortality

7

-

1.19 (0.41, 2.75)

aJapan

Akiba et al. (2012) [28]

200,583

1977-2002

1991-2002

12.2

1,373,000

Mortality

80

-1.93 (-6.12, 8.57)

-

Russia

Shilnikova et al. (2003) [25]

21,557

1948-1997

1948-1997

810 mGy

720,000

Mortality

66

1

b(0.5, 2)

-

  1. a all leukemia; b 90% CI; NC was no convergence of deviance after maximum iteration. CLL, chronic lymphocytic leukemia