Pesticide metabolite and oxidative stress in male farmers exposed to pesticide

Table 4 Linear regression analysis of pesticide metabolites and oxidative stress biomarkers

Independent variables	8-OHdG (μg/g creatinine)*			Isoprostane (ng/mg creatinine)*			MDA (μmol/g creatinine)*
Independent variables	B	ß	P-value	B	ß	P-value	B	ß	P-value
DMP*	0.238	0.320	0.020	0.329	0.396	0.003	0.320	0.432	0.001
DEP*	0.306	0.390	0.004	0.471	0.508	0.000	0.426	0.508	0.000
DMTP*	0.009	0.019	0.897	-0.020	-0.051	0.732	-0.001	-0.002	0.987
DETP*	0.207	0.082	0.015	0.342	0.504	0.000	0.180	0.329	0.014
PEM	0.029	0.302	0.020	0.040	0.434	0.000	0.015	0.195	0.155
CEI	0.001	0.297	0.020	0.001	0.213	0.106	0.000	0.182	0.171

Adjusted : age, smoking history, alcohol drinking, exercise
*Oxidative stress biomarker and pesticide metabolites : log transformation
Abbreviation: DMP (ug/g creatinine) ; dimethylphosphate, DEP (ug/g creatinine) ; diethylphosphate,
DMTP (ug/g creatinine) ; dimethylthiophosphate, DETP (ug/g creatinine) ; diethylthiophosphate
PEM Pesticide exposure month, CEI Cumulative exposure index

ISSN: 2052-4374