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Table 9 Meta-analysis of formaldehyde exposure and lymphohemtopoietic malignancies

From: Does formaldehyde have a causal association with nasopharyngeal cancer and leukaemia?

Authors, (Years)

Studies

Overall OR or RR (95% CI)

Collins et al. (2004) [53]

All studies for for leukemia

Industrial workers

Embalmers

Pathologists and anatomist

1.1 (1.0–1.2)

0.9 (0.8–1.0)

1.6 (1.2–2.0)

1.4 (1.0–1.4)

Bosetti et al. (2008) [37]

All LHM

 

Industrial workers

0.85 (0.74–0.96)

Professionals

1.31 (1.16–1.48)

Leukemia

 

Industrial workers

0.90 (0.75–1.07)

Professionals

1.39 (1.15–1.68)

Zhang et al. (2009) [54]

All LHM

All leukemia

Myeloid leukemia

Hodgkin lymphoma

Non-Hodgkin lymphoma

Multiple myeloma

1.25 (1.12–1.39)

1.54 (1.18–2.00)

1.90 (1.31–2.76)

1.23 (0.67–2.29)

1.08 (0.86–1.35)

1.31 (1.02–1.67)

Bachand et al. (2010) [38]

All leukemia

Professional/technical workers

Industrial workers

Myeloid leukemia

Lymphoid leukemia

1.05 (0.93–1.20)

1.28 (0.98–1.66)

0.99 (0.86–1.15)

1.09 (0.84–1.40)

1.11 (0.81–1.52)

Schwik et al. (2010) [55]

All leukemia

Professional workers

Industry workers

Healthy-worker effect adjusted

Myeloid leukemia

Healthy-worker effect adjusted

1.53 (1.11–2.21)

2.27 (1.15–4.45)

1.38 (0.96–1.99)

1.72 (1.18–2.51)

2.47 (1.42–4.27)

2.77 (1.39–5.52)

  1. LHM, Lymphohematopoietic malignancies