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Table 9 Meta-analysis of formaldehyde exposure and lymphohemtopoietic malignancies

From: Does formaldehyde have a causal association with nasopharyngeal cancer and leukaemia?

Authors, (Years) Studies Overall OR or RR (95% CI)
Collins et al. (2004) [53] All studies for for leukemia
Industrial workers
Embalmers
Pathologists and anatomist
1.1 (1.0–1.2)
0.9 (0.8–1.0)
1.6 (1.2–2.0)
1.4 (1.0–1.4)
Bosetti et al. (2008) [37] All LHM  
Industrial workers 0.85 (0.74–0.96)
Professionals 1.31 (1.16–1.48)
Leukemia  
Industrial workers 0.90 (0.75–1.07)
Professionals 1.39 (1.15–1.68)
Zhang et al. (2009) [54] All LHM
All leukemia
Myeloid leukemia
Hodgkin lymphoma
Non-Hodgkin lymphoma
Multiple myeloma
1.25 (1.12–1.39)
1.54 (1.18–2.00)
1.90 (1.31–2.76)
1.23 (0.67–2.29)
1.08 (0.86–1.35)
1.31 (1.02–1.67)
Bachand et al. (2010) [38] All leukemia
Professional/technical workers
Industrial workers
Myeloid leukemia
Lymphoid leukemia
1.05 (0.93–1.20)
1.28 (0.98–1.66)
0.99 (0.86–1.15)
1.09 (0.84–1.40)
1.11 (0.81–1.52)
Schwik et al. (2010) [55] All leukemia
Professional workers
Industry workers
Healthy-worker effect adjusted
Myeloid leukemia
Healthy-worker effect adjusted
1.53 (1.11–2.21)
2.27 (1.15–4.45)
1.38 (0.96–1.99)
1.72 (1.18–2.51)
2.47 (1.42–4.27)
2.77 (1.39–5.52)
  1. LHM, Lymphohematopoietic malignancies